• Pharmacy Lab

Low Dose Naltrexone

Updated: Dec 7, 2018

Low dose naltrexone (LDN) has been used to help with the symptoms of lupus, rheumatoid arthritis, multiple sclerosis, chronic pain, fibromyalgia, and many other conditions. Is it too good to be true, or is it the closest thing to a miracle that the medical community has seen lately?

Low Dose Naltrexone, a miracle for autoimmune diseases?

If low does naltrexone is so effective, why haven’t we heard more about it? Naltrexone is commercially manufactured as a 50mg tablet used to treat heroin, opiate, and alcohol addiction. Lower dosages, between 1.5mg and 4.5mg, show promise for autoimmune disorders. However, these low dose versions are not available from a manufacturer and therefore not widely publicized. In certain medical specialties LDN is well known, but there is not enough financial incentive for a drug manufacturer to produce and promote it.

Naltrexone can relieve pain and inflammation, as well as restore balance to the immune system.

LDN binds to the opioid receptors in your brain and other cells—the receptors that regulate the release of endorphins. This signals to your body that you are not getting enough natural endorphins, so you begin to produce more. By the time the naltrexone has worn off, opening the receptors again, your body has upped its endorphin production and you experience relief from your symptoms.

If someone you know is suffering with an autoimmune disease or suppressed immune response, share this article with them now.

How is Low Dose Nalterxone used?

Because LDN is not commercially available, you would need to obtain this medication from a compounding pharmacy where they will custom make a capsule based on your doctors order. Most patients start on a low dose, around 1.5mg, and work their way up over several weeks to their effective dose.  The usual dosages range from 1.5mg to 4.5mg once daily, but occasionally we see some a little lower or a little higher.

Doctor’s recommend a slow taper upwards of the dosage to avoid side effects and to easily determine the best dosage for each patient without having to give too much medication.  LDN is well tolerated, but some patients complain of sleep disturbance or vivid dreams when they first start on the medication.  These side effects usually subside or diminish after a week or two.

Other amazing results from LDN

New medical research has turned up even more uses for naltrexone.  A majority of burn patients who tried naltrexone capsules found relief from post-burn itching. Itching skin can be a major challenge for burn victims, and naltrexone offers a safe way to relieve this annoyance and promote faster healing by helping patients not to scratch their skin.

LDN can provide symptom relief for a variety of autoimmune disorders when used in conjunction with your primary treatment.

Our expert compounding pharmacists compound LDN without gluten, dyes, or other ingredients you may be sensitive to, as well as providing advice on how to get the best benefit from your LDN therapy.


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